Used Lab Equipment

Includes Installation and One Year Warranty (Preventative Maintenance at 6 months)

Method Development and Training also Available

Includes:

• AB Sciex API 3200 Mass Spectrometer LC/MS/MS
• Windows 7 Computer loaded w/ Analyst Software 1.5
• Turbo V-Spray ESI
• Vacuum pump
• Shimadzu Prominence 20 UFLC  Shimadzu
• Shimadzu DGU-20A3 Degasser
• (2)Shimadzu LC_20AD Liquid Chromatograph
• Shimadzu CTO Column Oven
• Shimadzu CBM-20A Communication Module
• CTC Autosampler
• Monitor – Mouse – Keyboard
• Manuals

The API 3200 LC/MS/MS system is a fully-integrated triple quadrupole mass spectrometer built using premier technology that combines sensitivity and selectivity with ruggedness and reliability, all in an affordable, compact package

• Innovative Turbo V ion source efficiently ionizes compounds over a wide range of flow rates, virtually eliminating cross-contamination, even with large sample loads
• Patented LINAC collision cell technology delivers superior MS/MS performance allowing faster scan times without compromising sensitivity or mass spectral quality
• Simplifies cross-platform methods transfer
• Gives meaningful results from every experiment

Specifications:

• Detector type: Pulse Counting CEM
• Dynamic Range: 5 orders of magnitude
• Ionization Sources: TurboIonSpray, APCI, DuoSpray, PhotoSpray
• Mass Accuracy / Stability: 0.1 Da over 8 hours and 0.15 Da over 24 hours
• Mass Range: 5-1,700 (Quad); 50-1,700 (LIT)
• Polarity Switching Time: 700 ms
• Scan Speed (Quad): 24,000 Da/sec
• Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, TripleTrap

Includes 1 year Service Contract, Installation, and a PM at 6 months

Method Development and Training also Available

Includes:

• AB Sciex API4000 LC/MS/MS
• Enhanced high performance triple quadrupole mass spectrometer system
• Line transformers
• Turbo V Ion Source (with APCI and ESI probes)
• Roughing Pump
• Windows 7 Computer loaded w/ Analyst Software 1.6
• Cart
• Shimadzu Prominence 20 UFLC  Shimadzu
  • Shimadzu DGU-20A3 Degasser
  • (2)Shimadzu LC_20AD Liquid Chromatograph
  • Shimadzu CTO Column Oven
  • Shimadzu CBM-20A Communication Module
• CTC Autosampler
• Monitor – Mouse – Keyboard
• Cables and Manuals

Specifications:

• Detector type: Pulse Counting CEM
• Dynamic Range: 5 orders of magnitude
• Ionization Sources: ESI, APCI
• Mass Accuracy / Stability: 0.1 Da over 8 hours, 0.15 Da over 24 hours
• Mass Range: 5-3,000
• Polarity Switching Time: 700 ms
• Scan Speed (Quad): 24,000 Da/sec
• Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM
• Sensitivity MRM Mode: 200 fg Reserpine on column: S/N > 1,200, C.V. < 5%

Includes:

• AB Sciex API4000 LC/MS/MS
• Enhanced high performance triple quadrupole mass spectrometer system
• Line transformers
• Turbo V Ion Source (with HESI probes)
• Roughing Pump
• Windows 7 Computer loaded w/ Analyst Software 1.6
• Cart
• Optional Shimadzu Front End
• Monitor – Mouse – Keyboard
• Cables and Manuals

Specifications:

• Detector type: Pulse Counting CEM
• Dynamic Range: 5 orders of magnitude
• Ionization Sources: ESI, APCI
• Mass Accuracy / Stability: 0.1 Da over 8 hours, 0.15 Da over 24 hours
• Mass Range: 5-3,000
• Polarity Switching Time: 700 ms
• Scan Speed (Quad): 24,000 Da/sec
• Scan Types: Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM
• Sensitivity MRM Mode: 200 fg Reserpine on column: S/N > 1,200, C.V. < 5%

Optional Shimadzu UFLC System Components:

• SIL-20AC
• LC-20AB
• CTO-20AC
• CBM-20A
• DGU-20A₅

The AB Sciex Triple Quad 4500 LC/MS has built upon the popular Sciex 4000 QQQ Mass Spectrometer platform and made it even better.  The Sciex 4500 has been redesigned with intelligence and performance in mind. This lcms brings you the best in quantitative sensitivity and robustness to expand upon the experiments going beyond MRM, and give you substantial improvements in data quality. The quadrupole mass spectrometer uses it’s quantitative and qualitative sensitivity to detect low analyte concentrations, a dynamic range for high to low concentrations, scan speed, and ionization source flow range. This potent lcms is equipped with Linear Ion Trap technology for more reliable quantitation over long runs.

The AB Sciex Triple Quad 4500 LC/MS is an ideal choice for research based labs dealing with regulated bioanalysis, targeted quantitative proteomics, clinical research, screening for contaminants in food or the environment, as well as ADME. The Sciex 4500 is also ideal for drug screen and pain management laboratories.  This triple quadrupole mass spectrometer has been designed from the inside out to offer a powerful tool that’s more compact to take up less valuable lab space. The triple quad 4500 is also an ideal choice for UHPLC, with fast precise quantitation and ultra-fast scan speeds. This quadrupole mass spectrometer has short dwell times, as low as 1 ms, and can scan for more compounds in a single experiment than ever before, using the powerful MRM program to automatically optimize your acquisitions.

The AB Sciex Triple Quad 4500 LC/MS use triple quads equipped with linear accelerator trap technology, that delivers up to a 100-fold increase to MS/MS sensitivity, and gives a more accurate detection, quantification and confirmation of compounds. The powerful Sciex lcms lets you acquire a complete MS/MS spectrum for every compound detected and cross references it with a built-in library for confirmation. With the computational power behind this LCMS, you’re able to develop new methods, and better streamline your existing work flow. The AB Sciex Triple Quad 4500 LC/MS also features QJet Ion Guide for better ion containment, AcQurate Pulse counting detector for improved extraction efficiency. Contact us today to learn more about our AB Sciex 4500 Triple Quadrupole LC/MS system.

Includes:

• AB Sciex 4500 LC/MS/MS
• Shimadzu Prominence 20 UFLC  
• Shimadzu DGU-20A3 Degasser
• (2)Shimadzu LC_20AD Liquid Chromatograph
• Shimadzu CTO-20AC Column Oven
• Shimadzu CBM-20A Communication Module
• SIL-20AC UFLC
• Windows 7 Computer Loaded with Analyst 1.6 Software       

Specifications:

• Sensitivity MRM: mode Reserpine 200 fg on column S/N > 2000  C.V. < 5%
• Maximum scan speed: 12,000 Da/sec
• Polarity switching time: 50 msec, in MRM and scheduled MRM (sMRM) modes
• Minimum MRM dwell time: 1 msec
• Mass range (m/z): 5-2000
• Cross talk for reserpine 609/195: <0.5% cross talk detectable with 2 msec dwell time and 3 msec inter-MRM pause time
• Triple quadrupole mass stability: 0.1 Da over 24 hours
• Scan types: Full scan MS and selected ion MS for both Q1 and Q3, product ion scan, precursor ion scan, neutral loss or gain scan, multiple reaction monitoring (MRM), and scheduled MRM (sMRM)
• Detector type: AcQuRate Pulse Counting CEM
• Dynamic range: 4 orders of magnitude
• Ionization sources: Turbo V source housing with TurboIonSpray probe or APCI probe.
• Maximum temperature: 750ºC
• Flow rate compatibility: 5 μL/minute to 3 mL/minute
• Power: 208V 50/60Hz AB Sciex 4500, 208V Vacuum Pump, 208V Peak N2 Generator, 115V Shimadzu UPLC
• Dimensions: 37" x 33" x 55" Sciex 4500
• Weight: 250lbs

This LCMS brings you the best in quantitative sensitivity and robustness to expand upon the experiments going beyond MRM, and give you substantial improvements in data quality.

Includes:

• AB Sciex 4500 LC/MS/MS
• Shimadzu Prominence 20 UFLC  
• Shimadzu DGU-20A3 Degasser
• (2)Shimadzu LC_20AD Liquid Chromatograph
• Shimadzu CTO-20AC Column Oven
• Shimadzu SIL-20AC UFLC
• Windows 7 Computer Loaded with Analyst 1.6 Software       

Specifications:

• Sensitivity MRM: mode Reserpine 200 fg on column S/N > 2000  C.V. < 5%
• Maximum scan speed: 12,000 Da/sec
• Polarity switching time: 50 msec, in MRM and scheduled MRM (sMRM) modes
• Minimum MRM dwell time: 1 msec
• Mass range (m/z): 5-2000
• Cross talk for reserpine 609/195: <0.5% cross talk detectable with 2 msec dwell time and 3 msec inter-MRM pause time
• Triple quadrupole mass stability: 0.1 Da over 24 hours
• Scan types: Full scan MS and selected ion MS for both Q1 and Q3, product ion scan, precursor ion scan, neutral loss or gain scan, multiple reaction monitoring (MRM), and scheduled MRM (sMRM)
• Detector type: AcQuRate Pulse Counting CEM
• Dynamic range: 4 orders of magnitude
• Ionization sources: Turbo V source housing with TurboIonSpray probe or APCI probe.
• Maximum temperature: 750ºC
• Flow rate compatibility: 5 μL/minute to 3 mL/minute
• Power: 208V 50/60Hz AB Sciex 4500, 208V Vacuum Pump, 208V Peak N2 Generator, 115V Shimadzu UPLC
• Dimensions: 37" x 33" x 55" Sciex 4500
• Weight: 250lbs

Includes One Year Service Contract, PM at 6 Months, and Installation

The AB SCIEX QTRAP 5500 System is a high sensitivity, bench top hybrid triple quadrupole-Linear Accelerator trap mass spectrometer designed for LC/MS/MS analyses. This instrument provides an uncompromised combination of Linear Accelerator trap and triple quadrupole functionality, uniquely allowing both  qualitative and quantitative analyses to be carried out in a single experiment.

Includes:

• AB Sciex 5500 Qtrap
• Shimadzu Prominence 20 UFLC  Shimadzu
  • Shimadzu DGU-20A3 Degasser
  • (2)Shimadzu LC_20AD Liquid Chromatograph
  • Shimadzu CTO Column Oven
  • Shimadzu CBM-20A Communication Module
  • CTC Autosampler
  • Computer Loaded with Analyst 1.6 Software       

Specifications

• Sensitivity MRM mode Reserpine: 50 fg on column S/N > 2000
• V.: < 5%
• Triple quad scan speed: 12,000 Da/sec
• Linear ion trap scan speed: 20,000 Da/sec
• Polarity switching time: 50 msec
• Minimum MRM Dwell Time: 1 msec
• Triple quad mass range (m/z): 5-1250
• Linear ion trap mass range (m/z): 50-1000
• Cross talk for Reserpine 609/195: No significant cross talk detectable with 1 msec dwell time and 3 msec inter-MRM pause time
• Triple quadrupole mass stability: 0.1 Da over 24 hours
• Scan types: Full scan MS and selected ion for both Q1 and Q3, product ion scan, precursor ion scan, neutral loss or gain scan, multiple reaction monitoring (MRM), enhanced MS scan, enhanced product ion scan, enhanced resolution scan, MS  scan, MRM3 scan, and TripleTrap™ scan modes

A proprietary band function enables obtaining accurate fractions even when the peak elution time varies, by catching the target component according to variations in the chromatogram. If connected to workstation software, fractions can be simulated on screen to determine whether or not the fraction program is appropriate.

Details:

• Small and Large Volume Collection Capacity
• The FRC-10A collects both analytical and preparative fractions. The standard configuration has a 144 5mL vial capacity. The large volume kit can be added for large volume collection.
• Precise Peltier Temperature Control
• For automated collection of thermally-labile fractions, Peltier temperature control keeps temperatures stable within a 4-70º C range.
• Simplified Graphical Parameter Entry
• Set up fractionation parameters graphically from the SCL-10AVP System Controller. Eliminate the guesswork of determining slope and level values.
• Fraction Collection Flexibility
• Tailor the collection to your application requirements.  Choose from collection criteria such as volume, threshold, and peak purity. A precise peak division feature ensures high purity fractions. The FRC-10A automatically adjusts for retention time shifts, so that only the peak of interest is collected. Our slope-override capability enables continued collection, even when the detector signal is off-scale.

Specifications:

• Drive System and Fraction Collection Methods: Arm-Movement X-Y System
• Select either solenoid valve or direct through nozzle
• Fraction Modes: Manual or programmed fraction collection by combining 14 types of parameters, such as slope, level, and band
• Number of Fractions: 16 to 144
• Collection Tubes: Glass: 3.5, 5, 20, 32, or 50 mL, or user supplied
• Polypropylene: 4.5, 5, 25, or 50 mL, or user supplied

Description:

System controller equipped with a data buffering function and acts as an interface for connecting LC workstations, network-client computers, and analytical instruments via Ethernet. Up to eight units can be connected to the box-type CBM-20A. The card-type CBM-20Alite is used by incorporating it into an LC-20A-Series solvent delivery pump or auto-sampler. It can control up to five units, including the unit in which it is incorporated.

Specifications:

Connectable Units:

Solvent delivery units: 4 max
Autosamplers: 1
Column ovens: 1
Detectors: 2 max
Fraction collectors: 1
Sub-controllers: 2 max."
Number of connectable units: 8 (expansion possible up to 12)
Data Buffering: Approx. 24 hours for one analysis (at 500 ms sampling rate; available only with LCsolution)
Event I/O: 4 inputs, 4 outputs
Analog Boards: Up to 2 boards can be mounted
Operating temperature range: 4°C to 35°C
Dimensions, weight: 260 (W) x 140 (H) x 420 (D) mm, 5.5 kg
Power requirements: 100 VAC, 100VA, 50/60HZ

Features:

• <400 uL internal volume
• Plugs into LC-20A/LC-30A series pump for power and control
• New material (Systec AF) allows high gas permeability
• Peak efficiency in under 1 minute
• Additional channel provided for autosampler rinse solution

Optional Computer Loaded w/ Clarity Software

Includes:

• Shimadzu DGU-20A3 Degasser
• (2)Shimadzu LC_20AD Liquid Chromatograph
• Shimadzu CTO Column Oven
• Shimadzu CBM-20A Communication Module
• SPD-20A Detector UV/vis Detector
• SIL-20A Auto Sampler

The chilled rackchanger unit exchanges the microplates on autosampler racks to enable samples to be continuously analyzed. 12 plates can be mounted inside the main unit and stored under refrigerated conditions.

Specifications:

• Method: Variable sample injection volume and total volume direct injection
• Injection Volume Range: 0.1 µL to 100 µL (0.1 µL to 2000 µL with option)
• Number of Samples Processed:
  • 175 (1-mL vials), 105 (1.5-mL vials), 50 (4-mL vials),
  • 192 (two 96-well MTP/DWP), 768 (two 384-well MTP/DWP)
  • *Twelve 96-well MTP/DWP in the rackchanger
• Injection Volume Precision: Max RSD 0.3 % (under specified conditions)
• Cross-Contamination: Max 0.005 % (naphthalene and chlorhexidine)
• Needle Rinsing: Freely settable, before or after sample injection

Specifications:

Site Requirements

• Dimensions (W x D x H): 416 × 379 × 274mm
• Weight: 11 kg
• Ambient temperature: 15 to 35°C
• Ambient humidity: 45 to 80%, less than 70% if over 30°C
• Power supply: 100~120 V 50/60 Hz 160 VA ; 220~240 V 50/60 Hz 160 VA

Performance Specifications:

• Spectrum bandwidth: 5 nm
• Wavelength accuracy: ± 1.0 nm
• Wavelength repeatability: ± 0.3 nm
• Stray light: less than 0.05% (220.0 nm Nal, 340.0 nm NaNO2 & UV39)
• Photometric range: −3.99 to 3.99 Abs (absorbance) ;  0.0 to 200% (transmittance)
• Recording range: −3.99 to 3.99 Abs (absorbance) ;  −399 to 399% (transmittance)
• Photometric accuracy: ± 0.005 Abs (at 1.0 Abs) ; ± 0.003 Abs (at 0.5 Abs)
• Photometric repeatability: ± 0.002 Abs (at 1.0 Abs)
• Drift: less than ± 0.001 Abs/h (after 2 hr warm-up)
• Baseline flatness: ± 0.010 Abs (after 1 hr warm-up, at 1100 to 200 nm)
• Noise: less than 0.002 Abs, Peak to Peak / less than 0.0005 Abs, RMS

Optical Design

• Wavelength range: 190.0 to 1100.0 nm
• Display wavelength: 0.1nm step
• Selectable wavelength: 0.1 nm step (1 nm step in spectrum mode)
• Scan speed: ± 3800 nm/min (wavelength change) ; ± 24 to 1400 nm/min (scan)
• Light source change: Auto change with wavelength ; halogen lamp only ; deuterium (D2) lamp only
• Measurement method: single beam measurement
• Monochromator: incorporates aberration-corrected concave blazed holographic grating
• Detector: silicon photodiode