Used Lab Equipment

Includes:
• G1311 Quarternary Pump or G1312A Binary Pump($1000 Less)
• G1329B Autosampler
• G1316A Column Compartment
• G4212B Dioade Array Detector
• Computer Loaded with OpenLab Software 
• Monitor – Mouse – Keyboard
• Cables and Manuals

The components can be customized to your needs.

The Agilent 1290 Infinity Binary LC is not only the most powerful but also the most adaptive UHPLC system available. No matter what your laboratory requires, the 1290 Infinity Binary LC can handle the widest range of applications; UHPLC methods, legacy HPLC methods, HPLC-to-UHPLC method transfer, method development, multi-compound screening, LC/MS coupling, and many more.

Features:

• Most adaptive  – emulates other HPLC and UPLC systems, connects to all Agilent and many non-Agilent software
• Highest performance & flexibility – by any measure
• HPLC-like service costs – UHPLC productivity

Includes:

• G1316C TTC Column Compartment
• G4226A Autosampler
• G1330B Autosampler Thermostat
• G4220A Binary pump
• Tray
• 1200 Instant Pilot

Description - The Waters 2790 features a large, easy-to-use LCD interface. Scientists can take advantage of the quick autostart and optimize their methods with a simple push of a button. Manage microplates with the built in autosampler. This reliable tool is a common work-horse in most analytical and contract labs. Built to meet labs rigorous requirements or routine analysis, this robust instrument is easily found in Pharmaceutical, Food Safety, R&D, Chemistry, Environmental or Quality Control labs. Simplify how you collect data, built-in compliance and validation features. The Empower software is capable of automating method development, archiving methods and customizing data reports.

Optional Detectors:

• 996 PDA Detector:
• 2996  PDA Detector:
• 2998 PDA Detector:
  
• 2487 UV detector:
• 2489 UV Detector:
  
• 2475 FLD detector:
  
• Waters 2410 Refractive Index Detector:
  

The components can be customized to your needs.

Includes Computer Loaded with 4000 Series Explorer Software Version 3.5.

The 4800 MALDI TOF/TOF Analyzer is a next-generation tandem time-of-flight MS/MS system that gives you all the advantages of MALDI in a flexible, easy-to-use, ultra-high-performance mass spectrometer.

• OptiBeam™ on-axis laser provides ten times greater sensitivity to identify and quantitate low-abundance proteins in complex biological samples.
• High-resolution precursor ion selection, enabled by the QuanTIS precursor selector, lets you detect and identify peptides that other systems miss and makes it easier for you to interpret your data by simplifying MS/MS spectra.
• Ideal solution for high sensitivity putative protein biomarker identification and quantitation.
• Fully supports LC MALDI workflows, allowing you to mass analyze without the time constraints of LC.
• Simple experiment setup and fast mass analysis maximizes laboratory productivity.
• High-energy, information-rich fragmentation patterns unavailable on other instrument platforms enable you to analyze carbohydrates, lipids, and other biological components.

Identify and Quantitate Putative Protein Biomarkers with Confidence
The 4800 MALDI TOF/TOF analyzer offers a new level of sensitivity for identifying and quantifying low abundance putative protein biomarkers. Fully compatible with novel iTRAQ™ reagents, the 4800 analyzer provides the most direct path to protein biomarker discovery. An expanded dynamic range enables high confidence identification and quantitation of low-level putative protein biomarkers in complex matrices. Powerful, easy-to-use GPS Explorer™ provides simplified, automated workflows to get you more quickly from discovery to validation.

The Only MALDI TOF/TOF™ Analyzer with On-Axis Laser Irradiation
The 4800 Analyzer is the only MALDI TOF/TOF mass spectrometer with on-axis laser irradiation, enabling sensitivity in the attamole range. Proprietary source modeling algorithms enable low ppm mass detection across the MALDI plate.

Expand Workflows, Increase Throughput
Get the speed, stability, and reliability you need to expand your current experimental workflows and add statistical significance to your experimental results. Quickly and easily increase throughput using automation features that allow you to rapidly and confidently collect the MS/MS spectra that really matter —and not waste valuable resources acquiring and evaluating those that don't.

Features:

The FlashGel System for fast electrophoresis of DNA is the ideal sample screening tool. Check up to 32 PCR or restriction fragments quickly without having to plan your day around agarose gels or verify your DNA sample integrity prior to downstream analysis. The FlashGel System is the fastest way to separate DNA and the best way to watch DNA migration as it happens. This revolutionary new tool separates DNA in 2 - 7 minutes. Monitor gel runs right at the bench, without UV light. The highly sensitive system allows a 5-20X reduction in DNA levels - saving both time and money.

Specifications:

• 5 minute separation and recovery

• See bands in as little as 2 minutes

• Recover samples directly without UV light band excision or purification,

• Real-time separation and documentation

• Watch band migration as it happens

• Photograph gels at the bench without DNA damaging UV light

• Outstanding sensitivity and resolution

Features:

The FlashGel Camera captures data from the FlashGel System and say goodbye to darkrooms and UV light. Complete separation and documentation safely, at your bench, in minutes. This simple digital camera in an enclosed hood connects directly to your laptop or PC via USB cable.

Specifications:

• 5 minute separation and recovery, See bands in as little as 2 minutes

• Recover samples directly without UV light band excision or purification

• Real-time separation and documentation

• Watch band migration as it happens

• Photograph gels at the bench without DNA damaging UV light

• Outstanding sensitivity and resolution

The Agilent 6420A Triple Quadrupole LC/MS System is equipped with performance specifications in Signal-to-Noise ratio and Instrument Detection Limit for routine analysis.

Specifications:

• MRM sensitivity Signal-to-Noise ratio (S/N) ESI positive: S/N > 6,000:1 Noise 1 × RMS
• MRM sensitivity Signal-to-Noise ratio (S/N) ESI negative: S/N > 2,000:1 Noise 1 × RMS
• MRM sensitivity Instrument Detection Limit (IDL) ESI positive: IDL < 60 fg
• MRM sensitivity Instrument Detection Limit (IDL) ESI negative: IDL < 60 fg
• Mass range: m/z 5 – 2,250
• Polarity switching: 30 ms
• Mass resolution (autotune):7 Da
• Mass resolution (manual tune):5 Da
• Mass accuracy:1 Da from 5 – 1,000 m/z; 0.01% from 1,000 – 2,000 m/z; 0.02% from 2,000 – 2,250 m/z
• Mass stability: < 0.1 Da in 24 h
• Dynamic range: > 6.0 × 106
• Scan modes: MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM
• Maximum scan rate: 12,500 Da/s
• Minimum MRM dwell time: 1 ms
• MRM transitions: 450 per time segment, > 40,000 ion transitions per method
• Dynamic MRM transitions: 4,000 ion transitions per method
• Triggered MRM transitions: Up to 10 MRM transitions (primary and secondary) for library search and compound confirmation
• Collision cell ion clearance: < 1 ms

Features:

• 1260 Infinity Binary Pump Clinical
• 1260 Infinity high perfomance degasser clinical edition
• 1260 Infinity high perfomrance autosampler clinical edition
• PEAK Nitrogen generator system

The Agilent 6460C Triple Quadrupole LC/MS System is equipped with Agilent Jet Stream Technology to enable enhanced sensitivity. The 6460 provides a fast and robust solution to simultaneously quantify, screen, and confirm analytes in the laboratory.

• Greater signal and reduced noise - Agilent Jet Stream technology uses super-heated nitrogen to improve ion generation and desolvation
• Efficient analysis – fast MRM speeds allow for analysis of over 100 overlapping compounds in a given retention time window
• Screen, confirm and quantify – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation
• Fast polarity switching for analysis of both positive and negative ions

Specifications:

• MRM sensitivity Signal-to-Noise ratio ESI positive: S/N > 30,000:1 Noise 1 × RMS
• MRM sensitivity Signal-to-Noise ratio (S/N) ESI negative: S/N > 10,000:1 Noise 1 × RMS
• MRM sensitivity Instrument Detection Limit (IDL) ESI positive: IDL < 12.5 fg
• MRM sensitivity Instrument Detection Limit (IDL) ESI negative: IDL < 12.5 fg
• Mass range: m/z 5 – 3,000
• Polarity switching: 30 ms
• Mass resolution (autotune):7 Da
• Mass resolution (manual tune):5 Da
• Mass accuracy:
  • Da from 5 – 1,000 m/z
  • 01% from 1,000 – 2,000 m/z
  • 02% from 2,000 – 3,000 m/z
• Mass stability: < 0.1 Da in 24 h
• Dynamic range: > 6.0 × 106
• Scan modes: MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM
• Maximum scan rate: 12,500 Da/s
• Minimum MRM dwell time: 1 ms
• MRM transitions: 450 per time segment > 40,000 ion transactions per method
• Dynamic MRM transitions: 4,000 ion transitions per method
• Triggered MRM transitions: Up to 10 MRM transitions (primary and secondary) for library search and compound confirmation
• Collision cell ion clearance: < 1 ms

Features:

The Agilent 6490 Triple Quadrupole LC/MS System incorporates iFunnel technology to give new levels of sensitivity for the most challenging quantitative analyses in pharmaceutical, clinical, food safety, and environmental applications. The quantitative power of the 6490 Triple Quadrupole is enhanced by an extended linear dynamic range.

The 6490 Triple Quadrupole LC/MS delivers:

• 10 X increase in sensitivity
• Up to six orders of linear dynamic range
• Robust performance and operation
• Zeptomole sensitivity for the most challenging applications

The 6490 triple quadrupole has a compact benchtop design, achieved through use of a curved collision cell. The newly designed cell also helps to reduce background noise, improving overall system signal-to-noise. New high frequency quadrupole electronics enable faster scan rates and allow for narrow mass window isolation.

Includes:

• Agilent 6490 LCMS Triple Quad System
• Agilent Varian MS40+ Vacuum Pump
• Computer loaded with Agilent Masshunter Workstation Software
• Monitor, Keyboard, Mouse, Cables

The 7890B Gas Chromatograph (GC) System is the world’s most widely used GC system. It features accurate temperature controls and precise injection systems, plus enhanced Electronic Pneumatic Control (EPC) modules for the best retention times.

Agilent 7890 GC-FID with Autoinjector, Headspace and MS detector.

The 7900HT Fast Real-Time PCR System is a real-time quantitative PCR system that combines 96- and 384-well plate compatibility and the TaqMan® Low Density Array with fully automated robotic loading-and now also offers optional Fast real-time PCR capability.

• Fast PCR option reduces run time to about 35 minutes in a standard 96-well format, or about 55 minutes in a 384-well plate
• Continuous wavelength detection from 500-660 nm allows the use of multiple fluorophores in a single reaction
• Measure gene expression levels, detect and quantitate pathogens, perform allelic discrimination (SNP genotyping) assays as well as score the presence of gene sequences
• 96- or 384-well plate compatibility (including the TaqMan® Low Density Array)
• Optional Enterprise edition software provides data analysis tools that support 21 CFR Part 11 guidelines providing data integrity and security
• Hands-free plate-loading and unloading provides true walkaway automation allowing you to increase your lab's productivity
• Proven assay development guidelines save time and money

Specifications:

• Calibrated Dye: SYBR® Green I, ROX™, NED™, JOE™, TAMRA™, VIC™, FAM™, TET™
• Capacity: Up to 84 x 384-well plates with optional automation accessory
• Detection Method: SYBR, Primer-Probe Detection
• Dimensions: 72 cm (W) x 84 cm (D) x 64 cm (H) (with drawer open)
• High-throughput Compatibility: High-throughput Compatible, Multiplexing
• Optics: Extended-life 488 nm argon-ion laser excitation source, No filters (CCD acts as spectrograph with continuous detection 500 -650 nm)
• Passive Reference Dye: ROX (Separate Tube), No ROX, Other Passive Reference Dye, ROX (Pre-mixed)
• Reaction Speed: Fast 
• Reaction Volume Range: 5-20 µl
• Run Time: 52 minutes (384-well in fast mode), <2 hrs (384-well in standard mode)
• Sample Ramp Rate: Fast mode: ± 3.0°C⁄sec, Standard mode: ± 1.6°C⁄sec
• Temperature Accuracy: ±0.25°C of display temperature
• Temperature Range (Metric): 4-100°C
• Temperature Uniformity: ±0.5°C
• Thermal Cycling System: Peltier-Based System
• Throughput: >5,000 real-time PCR rxns per day (384-well block and automation accessory), >10,000 endpoint PCR rxns per hour (384-well block and automation accessory)
• Weight: 114 kg (250 lbs) with automation accessory, 82 kg (180 lbs) without automation accessory
• Block Format: Interchangeable
• Dynamic Range: Up to 9 logs of linear dynamic range
• Sensitivity: Down to 10 copies

The Waters ACQUITY UPLC H-Class System delivers the flexibility of quaternary solvent blending with the advanced performance of UPLC® separations. The system's holistic design is targeted for routine analysis and method development use and is perfectly suited for running both HPLC and UPLC applications while still realizing the improved resolution and sensitivity of UPLC separations.

Includes:

• TUV Detector (PDA Detector $1000 additional)

• Sample Manager - FTN

• Column Manager to control up to 4 Columns
• Quaternary Solvent Manager
  • 15,000 psi up to 1.0 mL/min,
  • 9000 psi up to 2.0 mL/min
• Computer Loaded with Empower

Specifications:

• Dwell volume (total system): <400 ~L (includes standard 100 ~L mixer)
• Integrated leak management: Leak sensors, as standard, and safe leak handling
• Quantum synchronization: Injection synchronization between pump and sample manager enhances retention time reproducibility
• Set table flow rate range:
  • 01 0 to 2.000 mLlmin, in 0.001 mL increments (firmware version 1.5x and earlier)
  • 010 to 2.200 mL/min, in 0.001 mL increments (firmware version 1.60)
  • 001 to 2.200 mLlmin in 0.001 mL increments (firmware version 1.65 and later)
• Maximum operating pressure:
  • 15,000 psi up to 1.0 mL/min, 9000 psi up to 2.0 mL/min (firmware version l.5x and earlier)
  • 15,000 psi up to 1.0 mL/min, 7800 psi up to 2.2 mL/min (firmware version 1.6x and later)
• pH range: 2 to 12
• Unattended operation: Leak sensors and safe leak handling, full 96-hour diagnostic data display through console software
• Cycle time: <30s Inject to Inject

The Waters SQ Detector 2 is an advanced bench top single quadrupole mass detector designed for high performance LC/MS applications. With a wide range of ionization options including Atmospheric Pressure Photo Ionization (APPI) and the Atmospheric Solids Analysis Probe (ASAP), the SQ Detector is ideally suited to a wide range of qualitative and quantitative applications.  The system includes IntelliStart Technology, for automated system optimization and status monitoring, ensuring that the highest quality of data is routinely available to all levels of operators

Includes:

• Waters SQ Detector 2 UPLC/MS Mass Spectrometer
• Enhanced high performance single quadrupole mass spectrometer system
• Roughing Pump
• Windows 7 Computer loaded w/ Mass Lynx 4.1
• Optional Acquity UPLC
• Monitor – Mouse – Keyboard
• Cables and Manuals

Performance Specifications:

• Acquisition modes
  • Full scan MS
  • Selected Ion Recording (SIR)
• Radar: An information rich acquisition approach that allows you to collect highly specific quantitative date for targer compounds while providing the ability to visualize all other components
• Mass range: 2 to 3072 m/z
• Scan speed: Up to 15,000 Da/s
• Examples of achievable acquisition rates:
  • 15 scans per second (m/z 100 to 1000)
  • 30 scans per second (m/z 50 to 500)
• Mass stability: Mass drift is < 0.1 Da over a 24 hour period
• Linearity of response: The linearity of response relative to sample concentration for a specified compound is four orders of magnitude from the limit of detection
• Polarity switching time: 20 ms to switch between positive and negative ion modes
• EPCi mode switching time: 20ms to sqitch between ESI and APCI
• SIR acquisition rate: Minimum dwell time of 3 ms per SIR channel; Minimim inter-channel delay of 3ms
• Number of SIR channels: Up to 16,384 SIR channels (512 functions, 32 channels per function) can be monitored in a single acquisition; up to 1024 SIR channels when operating in GLP/secure mode (32 functions, 32 channels per function).
• Mass resolution: Automatically adjusted (Intellistart) to desired resolution.

Optional UPLC Sample Organizer

Optional Service Contract, Installation, and Training also available

The Waters ACQUITY UPLC System provides an integrated configuration for solvent and XYZZ sample management designed for use with ACQUITY UPLC chemistries. The core ACQUITY UPLC System comprises a Binary Solvent Manager, a Sample Manager with integral Column

Heater, and a Solvents Tray. The optional Sample Organizer is available for expanded sample capacity. The full line of Waters MS Technologies products, from single quadrupole to hybrid quadrupole time-of-flight are also available.

Includes:

• TUV Detector or PDA Detector ($1000 more)
• Sample Manager
• Column Heater (1 columns)
  • (Optional Column Manager to control up to 4 Columns $2000 extra)
• Binary Solvent Manager
  • 15000 psi Max Pressure
  • 1034 bars Max Pressure
• Computer Loaded with Empower

Includes 1 year Service Contract, Installation, and a PM at 6 months

Optional TUV or PDA Detector

Developed for integrated UPLC/MS/MS quantitative applications, the Waters ACQUITY TQD features the highest levels of tandem quadrupole MS selectivity, robustness, speed, and accuracy.   To maximize the analytical advantages of UltraPerformance LC (UPLC), the ACQUITY TQD operates at the highest data acquisition rates. When integrated with the ACQUITY UPLC System, the ACQUITY TQD gives you class-leading analytical detection limits, resolution, and sample throughput for all of your quantitative applications: bioanalysis, ADME screening, food safety, environmental monitoring, clinical, forensic, and more.

Includes:

• Waters TQD UPLC/MS/MS Mass Spectrometer
• Enhanced high performance triple quadrupole mass spectrometer system
• Roughing Pump
• Windows 7 Computer loaded w/ Mass Lynx 4.1 SCN 805.IVD
• Flex Cart for UPLC
• Waters Acquity UPLC
• Column Manager
• Sample Manager
• Binary Solvent Manager
• Monitor – Mouse – Keyboard
• Cables and Manuals

Performance Specifications:

• Acquisition modes
  • Full scan MS
  • Product ion scan
  • Precursor ion scan
  • Constant neutral loss
  • Selected Ion Recording (SIR)
  • Multiple Reaction Monitoring (MRM)
• Survey scan modes: Full scan MS triggered product ion scan
• Mass range: 2 to 2048 m/z
• Scan speed: Up to 10,000 Da/s
• Examples of achievable acquisition rates:
  • 10 scans per second (m/z 100 to 1000)
  • 20 scans per second (m/z 50 to 500)
• Mass stability: Mass drift is < 0.1 Da over a 24 hour period
• Linearity of response: The linearity of response relative to sample concentration for a specified compound is five orders of magnitude from the limit of detection
• Polarity switching time: 20 ms to switch between positive and negat ive ion modes
• MRM acquisition rate: Minimum dwell time of 3 ms per MRM channel
• Inter-channel cross talk: The inter-channel cross talk between two MRM transitions, acquired using an MRM dwell time of 10 ms and an inter-channel delay time of 10 ms, will be less than 0.02%.
• Number of MRM channels: Up to 16,384 MRM channels (512 functions, 32 channels per function) can be monitored in a single acquisition; up to 1024 MRM channels when operating in GLP/secure mode (32 functions, 32 channels per function).
• Mass resolution: Automatically adjusted (InteUiStart) to desired resolu tion; The vaUey between the 2034.63 Da and 2035.63 Da peaks is < 12% of the average height of the two peaks
• MRM sensitivity (ESI+) : A 1 pg on-column injection of reserpine will give a chromatographic signal-ta-noise greater than 2,000:1 (Gradient separation, LC mobile phase flow rate of 0.8 mL/min, MRM transition mil 609 > 195).
• MRM sensitivity (ESI-): A five pg loop injection of chloramphenicol, wi th a mobile phase flow rate of 200 ~lImin will give a chromatographic signal-ta-noise for the transition 321 > 152 mlz greater than 180: 1.
• MRM sensitivity (APCI+): A 100 pg loop injection of 17-a-hydroxyprogesterone, with a mobile phase flow rate of 1000 IJLlmin will give a chromatographic signal-ta-noise for the transition 331 > 109 mil > 150:1.