Description
The Advanced Analytical / Agilent Fragment Analyzer is a parallel capillary electrophoresis system engineered for automated separation, sizing, and quantification of nucleic acids. Equipped with a 12-capillary short array (33 cm effective length), the system performs high-resolution quality control (QC) of genomic DNA, total RNA, PCR fragments, and next-generation sequencing (NGS) libraries. By automating gel loading, sample injection, separation, and data analysis, the instrument streamlines sample preparation workflows while minimizing hands-on time and reagent consumption.
Features:
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Automated Parallel Electrophoresis: Simultaneously runs 12 capillary channels to process sample plates rapidly with high throughput.
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High-Sensitivity Laser-Induced Fluorescence: Detects low-concentration DNA/RNA fragments down to picogram levels without requiring large sample volumes.
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33 cm Short Capillary Array: Offers an optimal balance of fast run times (30 to 60 minutes per run) and high separation resolution.
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Versatile Assay Compatibility: Supports a broad array of pre-formulated reagent kits for RNA Quality Number (RQN) scoring, genomic DNA integrity, and NGS library sizing.
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Automated Gel & Buffer Handling: Performs automated capillary conditioning, gel switching, and post-run capillary washes between sample runs.
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Integrated Analysis Software: Uses ProSize analytical software to automatically calculate fragment sizes, molar concentrations, and sample quality metrics.
Specifications:
- Array Configuration: 12-Capillary Array (FA 12-Capillary Short)
- Capillary Array Length: 33 cm effective length/55 cm total length
- Sample Throughput: 12 samples per run (up to 288 samples per day)
- Detection Method: LED / Laser-Induced Fluorescence (LIF)
- Sample Input Volume: 1 uL to 10 uL required per well
- Sizing Resolution: Up to 1 to 2 bp for small fragments (under 500 bp)
- Operating Temperature: 15°C to 30°C (Controlled separation chamber)
- Dimensions (W x D x H): 61 x 61 x 61 cm (24 x 24 x 24 in)
- Electrical Requirements: 100-240 V AC, 50/60 Hz
- Weight: Approx. 38 kg (84 lbs)
