REPLIGEN KR2i Peristaltic Pump

Description

Single-use fully integrated benchtop TFF system for use in lab scale process development ranging from 2mL – 15L. Compatible with hollow fiber or flat sheet filters, this system offers many user-defined set-point controls so you can run complex applications in fully-automated modes.

KrosFlo KR2i TFF systems achieve an unparalleled combination of configurability and user-simplicity through modular, plug-and-play hardware. All components, either directly or indirectly, connect to the main pump, which then communicates with the KF Comm 2 software for control and monitoring. The Fully integrated KrosFlo KR2i TFF System features a digital peristaltic pump, graphical LCD display, digital pressure monitor, KR2i Pump head, automatic back pressure valve, filter module stand, and KF Comm real-time data collection software. 

Specifications;

KrosFlo TFF System:

• Filter Mode:                                                     Hollow Fiber                  Flat Sheet Cassettes
• Recommended Process Volume:              2 mL- 10 L                              12 mL – 15 L 
• Filter Surface Area:                                  13 cm²-3700 cm²                 100 cm² – 5000 cm²

• Main Drive / Feed Pump and Stand:
  • • • Easy-Load Pump Head-ip to 2.3 LPM (600 RPM)
      • Use with tubing sizes #13, #14, #16, #17, #18 and #25.
      • Integrated stand for hollow fibers

• Automatic Backpressure Control Valve (ABV): Controls user-set process TMP or permeate pressure
• Tablet as HMI: Microsoft Surface Pro with Krosflo RPM control and data acquisition software
• Auxiliary Pump: KorsFlo Junior, flowrates up to 0.3 LPM
• System Scales:
  • • • Maximum Weight: 20,000 g
      • Readability: 0.1 g
      • Platform Dimensions: 7.7” x 7.7” (17.8 cm x 17.8 cm)
• Enclosures: IP33 rated plastic enclosure. Wipe down cleanable. 
• Environmental Requirements: 
  • • • Operating Temperature: 0°C – 40°C
      • Relative Humidity: 10% – 90%

CTech FlowVPX System:

• Linear Range-Finger Technology: Automatically identifies linear region of absorbance data to verify compliance with Beer-Lambert Law 
• Flow Cell Volume: 
  • • • 3 mm Flow Cell: 0.9 mL
      • 10 mm Flow Cell: 9.0 mL

• Spectroscopic Engine: Agilent Cary 60
• Qualification Slope Range: 0.10 Au/mm to 46 Au/mm using NIST-traceable slope standards
• Qualification Slope Range: ±2%

• Maximum Pathlength:
  • • • 3 mm Flow Cell: 3.000 mm
      • 10 mm Flow Cell: 5.000 mm
      • Minimum Pathlength Step: 0.001 mm
      • Delivery Fiber Length: 3 m

KONDUiT Add-On Monitor

• Inputs: 2 Conductivity Inputs, 2 Temperature Inputs
• Sensor Size: ¼” HB and ½” HB
• Conductivity Range: 0.1 to 100 mS/cm

• Conductivity Accuracy:
  • • • 0.1 mS/cm–2 mS/cm: ±0.1 mS/cm
      • 2 mS/cm–50 mS/cm: ±5%
      • 50 mS/cm–100 mS/cm: ±5% (Typical)
      • Temperature Range: 0°C–70°C
      • Temperature Accuracy: ±0.2°C or better

Auxiliary Components:

• Pressure transducer: 

• • • Up to 3 single-use sensors
    • Pressure Range: -7 to 75 psi (-0.48 to 5.2 bar)
    • Polysulfone, luer-style ports

• Tubing: PharmaPure, TPE, size #14 and #16
• Stand: Integrated stand with hollow fiber holder
• Auxiliary Component Octopus cable: Allows for connectivity of scales, auxiliary pumps, and KONDUiT System
• Reservoirs (Optional): 15 mL, 50 mL, 250 mL, 500 mL polypropylene conical containers, caps with ported inlets, conical holders
• High-Performance pump head(Optional): 

• • High-performance pump head, up to 2.9 LPM
  • For use with tubing sizes #15, #24, #35, and #36
  • Note: Pump will accept up to two (2) pump heads

Power Requirements:

• KR2i System: 
  • • • Supply voltage: 90–260 Vrms @ 50/60 Hz (universal input)
      • Max current: 2.2 A @ 115 Vrms or 1.1 A @ 230 Vrms

• Cary 60: 90 VAC–265 VAC, frequency 47 Hz–63 Hz
• VPX power input: 24 VDC, 0.6 A max current draw
• KONDUiT: 
  • • • Input power supply range: 100 VAC–240 VAC
      • Input Frequency: 47 Hz–63 Hz
      • KONDUiT Power input: 24 VDC, 0.625 A max current draw
• FlowVPX:
  • • • Power supply input: 100 VAC–230 VACFrequency: 50 Hz–60 Hz

General:

• Dimensions: 
  • • • KR2i Main pump: 267 × 203 × 203 mm (10.5” × 8” × 8”)
      • Auxiliary Pumps (2): 140 x 178 x 160 mm (5.5” x 7” x 6.3”)
      • KONDUiT: 197 x 120 x 114 mm (7.75” x 4.75” x 4.5”)
      • Scales (2): 330 x 203 x 97 mm (13” x 8” x 3.8”)
      • FlowVPX: 120 x 100 x 230 mm (4.72” x 3.94” x 9.06”)
      • Cary 60: 483 x 559 x 203 mm (22” x 8” x 19”)

• Weights: 
  • • • KR2i Main pump: 5.9 kg (13 lb)
      • Auxiliary Pumps (ea): 2.2 kg (4.8 lb)
      • Konduit: 1.6 kg (3.53 lb)
      • Scales (ea): 2.7 kg (6 lb)
      • Cary 60: 18.1 kg (40lb)
      • FlowVPX (3 mm flow cell): 4.31 kg (9.5 lb)